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In placebo-controlled clinical trials across indications from baseline to endpoint, duloxetine treatment was associated with mean increases of 0.5 mm Hg in systolic blood pressure and 0.8 mm Hg in diastolic blood pressure compared to mean decreases of 0.6 mm Hg systolic and 0.3 mm Hg diastolic in placebo-treated patients. There was no significant difference in the frequency of sustained 3 consecutive visits elevated blood pressure. In a clinical pharmacology study designed to evaluate the effects of duloxetine on various parameters, including blood pressure at supratherapeutic doses with an accelerated dose titration, there was evidence of increases in supine blood pressure at doses up to 200 mg twice daily. At the highest 200 mg twice daily dose, the increase in mean pulse rate was 5.0 to 6.8 beats and increases in mean blood pressure were 4.7 to 6.8 mm Hg systolic and 4.5 to 7 mm Hg diastolic up to 12 hours after dosing. I am doing this alone. why? THERE IS NOT ONE PROVIDER OUT THERE. THERE IS NOT ONE PHARMACIST OUT THERE. NOT EVEN Eli Lilly the maker of the SHIT can tell me how long this is going to last.
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