I have had Mirena now for almost a year and about a month ago started to develop pain and swelling in my ankles. It became so painful that I was unable to get out of bed without help from my husband. My primary care physician initially thought that I injured myself working out but when my symptoms worsened he referred me to a Rheumatologist who still has not diagnosed me with anything. My blood tests showed imflammation and I have a follow up this month. However, the pain is gone and now I have mild swelling in my ankles. I am seriously considering getting the Mirena removed because like you, after reading all of these messages I feel it is causing my problems too.