I have been taking zantres3 for about 10days, i have lost about 5 pounds but i workout 1 hour 3days a week (water aerobics too. I have the dryness around my eyes, was nauseated,loss appetite etc. but now I have cut down from 4 a day to 2 a day because i am eating less. Hang in ther guys, don\'t give up, I think the key is focus,endurance, prayer and a plan.