I have been on effexor for 2 years increased over time from 75 mg to now 300mg.I have been the worst now with depression than ever and I personaly think its the high dose causing it. I am not finishing meds all together, just canging to a different one as 2 days ago I was having sceaming fits and smashing my head up against the car window, my partner was fearful and I was scared of myself.I have worse depression now than before Effexor.I have not taken it for 1 day before I start on new drug and withdrawals are on there way today my head is closing in, becoming foggy. Effexor is an EVIL drug all round. Pass this on to people please.