Totally agree with all that you have commented on the horrible effects of coming off of Effexor. I\'m currently on it and fear coming off of it, because I have gone through the horrible things you\'ve mentioned with just inadvertently missing a dose here or there. It\'s horrible, when I\'ve missed doses, even one I feel really anxious, unable to concentrate well, almost indecisive about things, shaky, stomach is queezy and uneasy, diarehea, horrible and very vivid dreams, etc. etc. etc. I asked my pharmacist the last time I picked up my prescrip. how I would attempt coming off of it and she said usually the dr.\'s cut down the dose, but gheesh if what you guys are saying about going from 150 to 75 and still having those affects, I doubt I\'d want to do that, but there isn\'t anything in between 75 and 150 is there? I took Zoloft before this and came off of that very easily with no effects on me at all, what a change this stuff is. Oh and I second who ever it was that mentioned weight gain....that\'s definitely one thing I\'ve experienced too and it\'s awful!!