But what do you do When it’s the only thing that works? I mean without it I’m doomed to death by suicide with it I’m relegated to a life where I don’t feel much, can’t have normal sex, life seems boring at best. Even though I take 300mg of effexor and 45mg of remeron daily plus other drugs for bipolar, I have still had to undergo over a year of ECT. I’m sorry it’s been over 3 days since my last effexor fix due to a glitch at my drug store and my head is very muddled. I fell like I’m coming undone.